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Elizabeth (Izzy) Bell – Directed evolution of PETase: a plastic degrading enzyme Author: Emilie Brady Added on Wed Oct 28 08:29:00 GMT 2020 Duration: 0:04:37 Izzy is a 3rd year PhD student in Anthony Green’s group and is working with PETase, an enzyme that degrades polyethylene terephthalate (PET) plastic. In its natural state, the enzyme is not very active or stable so would not be suitable for use in a large-scale recycling process. Through the use of directed evolution, Izzy has engineered the PETase to be more thermostable and active at 65 degrees. The aim is to continue evolving the enzyme to make it stable at 70 degrees, so that it can be used for industrial scale plastic recycling.  

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